Micropatterned Protective Membranes Inhibit Lens Epithelial Cell Migration in Posterior Capsule Opacification Model (2015)
During development of the ClearSight™ IOL, Sharklet researched the effect that micropatterned surfaces have on epithelial cells. After surgery to remove cataracts, an intraocular lens is inserted into the eye. Epithelial cells migrate onto the new lens, resulting in posterior capsule opacification (PCO). A followup surgery uses a laser to remove these migrated cells. The ClearSight IOL would feature a protective ring of Sharklet to prevent the cellular migration and negate the need for the laser procedure. Read More
Microtopographies Inhibit Human Lens Epithelial Cell Migration in Posterior Opacification Model (2014)
In this study, Sharklet tested the micropattern’s ability to limit cell migration.